The ALODOX Convenience Kit contains ALODOX Tablets (Doxycycline Hyclate 20 mg), OCuSOFT Lid Scrub PLUS Extra Strength Pre‐Moistened Pads (30 ct.), OCuSOFT Lid Scrub Original Foaming Eyelid Cleanser (50 mL), Tranquileyes Moist Heat Therapy Goggles (limited use trial) and Thermoeyes instant, reusable heat packs.

As prescribed by your doctor, the ALODOX Convenience Kit works by combining four essential components of eyelid therapy and hygiene into one convenient package for effective relief.

• 1) Address inflammation with low dose doxycycline
• 2) Remove harmful bacteria with an extra strength eyelid cleanser
• 3) Maintain eyelid hygiene daily with a mild cleanser
• 4) Relieve irritation and discomfort with a warm compress

For best results, follow these 4 simple steps.

Doxycycline is a tetracycline antibiotic. It works by slowing the growth of bacteria in the body and reducing inflammation.

Low dose doxycycline provides the same anti‐inflammatory power of higher dose doxycycline with fewer side effects. Most bacteria found on the eyelids are resistant to doxy cycline, but studies have demonstrated that using lower doses of doxycycline reduces inflammation without concerns of bacterial resistance.^1,2

Without proper eyelid hygiene, conditions resulting in inflammation of the eyelids and dry eyes can develop. For moderate to severe cases of eyelid disease, the ALODOX Convenience Kit may help prevent or drastically reduce inflammation by removing oil and debris from the eyelids, employing the use of an oral antibiotic as well as an antibacterial cleanser and warm compress. ALODOX is indicated to reduce the development of drug‐resistant bacteria while maintaining the effectiveness of Doxycycline Hyclate Tablets. ALODOX should only be used to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

The recommended dosage is 20 mg twice per day. Take ALODOX tablets as prescribed by your doctor. The following suggestions are important when taking doxycycline pills to minimize stomach upset:

• 1) Do NOT take pills before lying down (wait at least 30 minutes before lying down)
• 2) Do NOT take pills with anything but water (acidic beverages such as orange juice or even coffee may cause stomach problems in combination with doxycycline)
• 3) DO take pills with meals (provided there are not a lot of dairy products in your meal)

ALODOX is a prescription medication, use only as directed.

It usually takes about 4‐6 weeks before the results of using ALODOX are noticeable. Even if symptoms disappear, continue to use the medication for the full time prescribed to prevent the return of infection. Inform your doctor if your condition persists or worsens.

The ALODOX Convenience Kit is available by prescription only. If you think you could benefit from ALODOX, ask your eye doctor to write a prescription for this convenient kit.

You can assist your Pharmacist in ordering the ALODOX Convenience Kit from their Wholesale Distributor by providing him/her with the following number and wholesalers. NDC 54799 ‐      534‐66
Amerisource       600325
Cardinal        3988052
McKesson        1640390

ALODOX is contraindicated in persons who have shown hypersensitivity to doxycycline or any of the other tetracyclines. Doxycycline can cause fetal harm when administered to a pregnant woman. The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of the teeth. Tetracycline drugs should not be used during tooth development or in pregnant or nursing mothers. Photosensitivity can occur with any tetracycline class drugs.

Yes, OCuSOFT Lid Scrub Original is available at most national retail locations, including Walgreens, CVS, Wal‐Mart , Rite Aid and Duane Reade. OCuSOFT Lid Scrub PLUS is available at Walgreens, CVS, Duane Reade and many other fine retailers. Tranquileyes Moist Heat Therapy Goggles are only available through eye care professionals. If your eye doctor is out of stock, ask him/her to order directly from OCuSOFT on your behalf.

Simply remove and moisten the soft sponge from the Tranquileyes Goggles, insert the activated Thermoeyes gel packs, replace the sponge or vice versa and wear over closed eyes for approximately 15‐20 minutes. Thermoeyes heat packs are reusable up to 100 times. To reset, simply boil in water for 3‐5 minutes. Once cooled to room temperature, Thermoeyes are again ready for use as previously directed. For complete instructions, please click here. (link to second page of Tranquileyes detail sheet)

1. Data on file (Periostat NDA, Section 6: Human Pharmacokinetics and Bioavailability), CollaGenex Pharm., Inc.
2. Burns F, Stack M, Gray R, et al. Inhibition of purified collagenase from alkaline‐burned rabbit corneas. Invest Ophthalmol Vis Sci. 1989;30:1569‐1575.

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